Uterine fibroids (also called leiomyomas or myomas) in 99% of cases are noncancerous tumors that grow in or on the uterus.
They are made of muscle and fibrous tissue and vary in size: from tiny seedlings to large masses that can distort the uterus.
Most fibroids are benign, meaning they rarely turn cancerous (<1% of cases).
Fibroids can be asymptomatic, but when symptoms appear, they often include:
Heavy menstrual bleeding or prolonged periods
Spotting
Bleeding between periods
Anemia
Cramps
Pelvic pain, lower back pain
Pressure, or bloating; feeling full in the abdomen, swelling
Leg pains
Frequent urination
Constipation
Fatigue (often from anemia)
Pain or discomfort during intercourse
Infertility or pregnancy complications
Emotional distress and decreased quality of life
Types of Fibroids:
Location: Grow within the muscular wall of the uterus.
Key point: This is the most common type.
Symptoms: Can cause heavy bleeding, pelvic pain, or pressure on nearby organs if large.
Location: Grow just underneath the lining (endometrium) of the uterus and may extend into the uterine cavity.
Key point: Even small ones can cause big symptoms.
Symptoms: Heavy and prolonged periods, fertility issues, or repeated miscarriages.
Location: Grow on the outer wall of the uterus, bulging outward.
Key point: Usually don’t affect menstrual flow.
Symptoms: Can press on the bladder or bowel, causing frequent urination, constipation, or back pain.
Location: Grow on a stalk (a thin stem-like structure) that attaches to either the inside or outside of the uterus.
Key point: They can sometimes twist, causing sharp pain.
Symptoms: Pain or pressure, depending on position.
Location: Grow in the cervix (the lower part of the uterus that connects to the vagina).
Key point: Rare compared to other types.
Symptoms: Can cause issues with urination, sexual intercourse, or childbirth.
6. Calcified Fibroids
Old, dead, regenerated, non-active fibroids that have hardened with calcium deposits. They usually don’t cause serious problems and often don’t require treatment unless they press on nearby organs or cause discomfort.
Up to 70-80% of women develop fibroids by age 50.
Most commonly diagnosed in women aged 30-49, fibroids can occur anytime during the reproductive years (18-50).
Risk factors include genetics, obesity, early menstruation, and vitamin D deficiency.
Having children lowers a woman’s risk of developing fibroids, and the risk decreases further with each additional pregnancy.
Options vary depending on size, location, symptoms, and reproductive goals:
1. Watchful Waiting (Monitoring)
For women with no or mild symptoms.
Fibroids may shrink after menopause.
Regular ultrasounds and check-ups.
2. Medications
Hormonal treatments (help control symptoms, not cure fibroids):
GnRH agonists (e.g., Lupron) → shrink fibroids temporarily, often used before surgery.
GnRH antagonists (e.g., Oriahnn, Myfembree) → newer meds that shrink fibroids and control heavy bleeding.
Progestin-releasing IUD → reduces heavy bleeding, but doesn’t shrink fibroids.
Oral contraceptives → help control bleeding, not shrinkage.
Tranexamic acid (Lysteda) → non-hormonal, reduces heavy periods.
Iron supplements → for anemia caused by heavy bleeding.
3. Minimally Invasive Procedures
Uterine Artery Embolization (UAE / UFE) → blocks blood supply to fibroids, causing them to shrink.
MRI-Guided Focused Ultrasound Surgery (FUS) → high-intensity ultrasound waves destroy fibroid tissue without incision.
Radiofrequency Ablation (Acessa, Sonata) → heat energy shrinks fibroids.
4. Surgical Options
Myomectomy (removal of fibroids, uterus preserved):
Hysteroscopic (through vagina, for submucosal fibroids).
Laparoscopic / Robotic (small incisions).
Abdominal (open surgery, for large/multiple fibroids).
Hysterectomy (removal of uterus):
Permanent solution, no recurrence.
Ends the ability to have children.
Alternative / Complementary Approaches
(Not cures, but may help with symptoms, inflammation, or hormone balance. Effectiveness varies.)
1. Lifestyle & Natural Supports
Dietary changes: more fruits, vegetables, whole grains; reduce red meat and processed foods.
Exercise & weight management → helps regulate hormones.
Stress reduction → yoga, meditation, breathing exercises.
2. Supplements & Herbal Supports (consult a doctor before use)
Green tea extract (EGCG) → studied for reducing fibroid size.
Vitamin D → low levels linked to fibroid growth.
Turmeric/Curcumin → anti-inflammatory.
Milk thistle → supports liver detox.
Omega-3 fatty acids → anti-inflammatory.
3. Traditional / Integrative Medicine
Acupuncture → may help with pain and pelvic circulation.
Chinese herbal medicine → blends aimed at hormone balance and symptom relief.
Ayurveda → herbal formulas and detox practices for reproductive health.
Fibroids are the leading cause of hysterectomy worldwide, with 40-50% of treated women eventually having the procedure.
They affect millions of women’s daily lives, causing chronic pain, missed work, emotional strain, and fertility challenges.
About 26 million women in the U.S. have fibroids
28% report fibroids affect career potential
Despite prevalence, fibroids remain under-discussed, under-researched, and under-funded.
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